Publications

 

Works about Pathological Anatomy

SOARES IC, SIMÕES K, SOUZA JES, WAKAMATSU A, CIRQUEIRA CS, OKAMATO OK, TUMA MC, ALVES VAF. Evaluation of four monoclonal antibodies of oncological interest in renal carcinomas. Histopathology 2010;57(suppl 1):257:716. XXVIII International Congress of the International Academy of Pathology. Transamérica Hotel Conference Center, São Paulo – Brazil, 11 a 15 de october de 2010.

 

 

SIMÕES K, SOARES IC, WAKAMATSU A, OKAMOTO KO, ALVES VAF. Lewis B (LeB) antigen expression is lower in breast carcinoma and is associated with hormone receptor status and histological type. Clinics 2010;65 (supl 6):S54 – 46. 4o Simpósio Avanços em Pesquisas Médicas – LIM Laboratórios de investigação Médica HC-FMUSP. Centro de Convenções Rebouças, 30 de September e 01 de october de 2010

 

SOARES IC, SIMÕES K, SOUZA JES, WAKAMATSU A, CIRQUEIRA CS, OKAMOTO OK, TUMA MC, ALVES VAF. Evaluation of four monoclonal antibodies of oncological interest in renal carcinomas. Clinics 2010;65 (supl 6):S55 – 50. 4o Simpósio Avanços em Pesquisas Médicas – LIM Laboratórios de investigação Médica HC-FMUSP. Centro de Convenções Rebouças, 30 de September e 01 de october de 2010

 

SIMÕES K, SOARES IC, WAKAMATSU A, OKAMOTO OK, JUNGBLUTHJAA, ALVES VAF, OLD LJ. Lewis B (LeB) antigen expression is lower in Breast Carcinoma an is associated with hormone receptor status and histological type. Mod Pathol 2009;22(supl 1):342A (1552) 98th Annual Meeting. United States and Canadian Academy of Pathology. Boston, Massachusetts, 07 a 13 de march de 2009.

 

SOARES IC, SIMÕES K, WAKAMATSU A, OKAMOTO OK, PONTES J, JUNGBLUTH AA, ALVES VAF, OLD LJ. Expression patterns of Lewis Y antigen in prostate tissue: Non-neoplastic, primary Adenocarcinoma and bone metastasis. Mod Pathol 2009;22(supl 1):155A (695) 98th Annual Meeting. United States and Canadian Academy of Pathology. Boston, Massachusetts, 07 a 13 de march de 2009.

 

SOARES IC, ESPÍRITO SANTO KS, WAKAMATSU A, RÉSSIO RA, SOUZA SJ, SOUZA JES, OKAMOTO OK, ALVES V. Immunohistochemical characterization of ovarian carcinoma with monoclonal antibody MX35. Histopathology 2008;53(Suppl. 1):180-181 (410). XXVIITH International Congress of the International Academy of Pathology. Atenas, Grécia, 12 a 17 de october de 2008. JCR: 3.2160

 

SOARES IC, ESPÍRITO SANTO KS, PONTES JR J, JUNGBLUTH AA, WAKAMATSU A, OKAMOTO OK, ALVES VAF, OLD LJ. Expression of Lewis Y antigen in prostate tissue: Non-neoplastic, primary adenocarcinoma and bone metastasis. A tissue microarray study. Annals of the XI São Paulo Research Conference – Medicina Molecular e Farmacogenética, 21 (01.018) XI São Paulo Research Conferences. Medicina Molecular e Farmacogenética. São Paulo, SP, 18 a 20 de september de 2008.

SIMÕES K, SOARES IC, SCAPULATEMPO C, JUNGBLUTH AA, RITTER G, OKAMOTO OK, WAKAMATSU A, ALVES VAF. Lewis B (LeB) antigen expression in colorectal carcinoma – A tissue microarray (TMA) study. Modern Pathology 2008;21(supl 1):136A (617). 97TH Annual Meeting of the United States and Canadian Academy of Pathology. Denver, Colorado, U.S.A – 01 a 07 de march de 2008. JCR: 3.7530

 

ESPIRITO SANTO KS, SOARES IC, SCAPULATEMPO C, WAKAMATSU A, OKAMOTO OK, ALVES VAF. Lewis B (LEB) antigen expression in colorectal carcinoma: a tissue microarray (TMA) study. J Bras Patol, 2007; 43(5):89 (09.46). XXVI Congresso Brasileiro de Patologia. Bento Gonçalves, RS. 14 a 17 de november de 2007.

SOARES IC, ESPIRITO SANTO KS, WAKAMATSU A, OKAMOTO OK, ALVES VAF. Immunohistochemical characterization of monoclonal antibody MX35 on ovarian carcinoma. J Bras Patol, 2007; 43(5):72 (08.24). XXVI Congresso Brasileiro de Patologia. Bento Gonçalves, RS. 14 a 17 de november de 2007. ESPÍRITO SANTO KS, SOARES IC, SCAPULATEMPO C, WAKAMATSU A, OKAMOTO K, ALVES VAF. Lewis B antigen expression in colorectal carcinoma – A tissue microarray study. Clinics, 2007; 62(supl 3):S58 (PO 462) 3o Simpósio Avanços em Pesquisas Médicas. Centro de Convenções Rebouças, São Paulo, 27 a 28 de september de 2007. pISSN: 1807-5932

SOARES IC, ESPÍRITO SANTO KS, WAKAMATSU A, OKAMOTO OK, ALVES VAF. Immunohistochemical characterization of monoclonal antibody MX35A on ovarian carcinoma. Clinics, 2007; 62(supl 3):S57 (PO 460) 3o Simpósio Avanços em Pesquisas Médicas. Centro de Convenções Rebouças, São Paulo, 27 a 28 de september de 2007. pISSN: 1807-5932

 

Works about cell lines development for production of humanized antibodies

Yeda, FP; Santos, ML; Tsuruta LR; Horta, BB; Pimenta Jr. AA; Ritter, G; Moro, AM. Humanized anti-NaPi2b Monoclonal Antibody- Cell Line Generation. In: IBC 7th Cell Line Generation and Engineering, Boston, USA, 8-10 June, 2011. Santos, ML; Yeda, FP; Tsuruta LR; Horta, BB; Pimenta Jr. AA; Ritter, G; MORO, AM. Generation of a Stable Cell Line for Rebmab200 MAb. In: 22nd ESACT Meeting, 2011, Vienna. ESACT 2011 Abstract Book. Vienna, Austria, 15-18 May, 2011. p. 67. Santos, ML; Pimenta Jr. AA; Pavanelli AC; Schmidt, MCB; Old, LJ; Smaletz O; Moro, AM. Stability analysis of humanized Rebmab100 monoclonal antibody. In: 9th PEACe Conference on Protein Expression in Animal Cells, Jackson Hole, WY, USA, 19-23 September 2009, p. 163. Santos, ML; Pavanelli AC; Degaki TL; Inocêncio, AL; Tsuruta LR; Travassos, LRR; Old, LJ; Ritter, G; MORO, AM. Flow Cytometry Characterization of Rebmab200. In: 9th PEACe Conference on Protein Expression in Animal Cells, 2009, Jackson Hole, WY, USA, 19-23 September 2009, p. 129. Degaki TL; Pimenta Jr. AA; Tsuruta LR; Targino, RC; Old, LJ; Ritter, G; Okamoto, OK; MORO, AM. Generation of Humanized Rebmab200. In: 9th PEACe Conference on Protein Expression in Animal Cells, 2009, Jackson Hole, WY, USA, 19-23 September 2009, p.133. Dos Santos ML, Yeda FP, Tsuruta LR, Horta BB, Pimenta AA Jr, Degaki TL, Soares IC, Tuma MC, Okamoto OK, Alves VA, Old LJ, Ritter G, Moro AM. Rebmab200, a Humanized Monoclonal Antibody Targeting the Sodium Phosphate Transporter NaPi2b Displays Strong Immune Mediated Cytotoxicity against Cancer: A Novel Reagent for Targeted Antibody Therapy of Cancer. PLoS One. 2013 Jul 31;8(7):e70332. doi: 10.1371/journal.pone.0070332. Print 2013.

 

Works about Clinical Trials

Oren Smaletz, Maria D.P.E. Diz, Claudio C. do Carmo, Jorge Sabbaga, Geraldo F. Cunha-Junior, Sergio J. Azevedo, Fernando C. Maluf, Carlos H. Barrios, Ronaldo L. Costa, Ana G. Fontana, Vivian Madrigal, Alberto J. Wainstein, Fernanda P. Yeda, Venâncio A. Alves, Ana M. Moro, Roberto Blasbalg, Andrew M. Scott, Eric W. Hoffman A phase II trial with anti-Lewis-Y monoclonal antibody (hu3S193) for the treatment of platinum resistant/refractory ovarian, fallopian tube and primary peritoneal carcinoma. Click here to access summary.

O. Smaletz, M. D. P. Diz, C. C. Carmo, J. Sabbaga, G. F. Cunha, S. J. Azevedo, F. C. Maluf, C. H. Barrios, R. L. Costa, A. G. Fontana, V. A. Alves, A. M. Moro, A. M. Scott, E. W. Hoffman, L. J. Old; “Anti-LeY monoclonal antibody (mAb) hu3S193 (Rebmab100) in patients with advanced platinum resistant/refractory (PRR) ovarian cancer (OC), primary peritoneal cancer (PPC), or fallopian tube cancer (FTC)”; Chicago, Ill. June 4-8, 2011 ASCO Annual Meeting.

Soares IC, Simões K, de Souza JE, Okamoto OK, Wakamatsu A, Tuma M, Ritter G, Alves VA.2012. In silico analysis and immunohistochemical characterization of NaPi2b protein expression in ovarian carcinoma with monoclonal antibody Mx35. ApplImmunohistochem Mol Morphol. 2012 Mar;20(2):165-72. Click here to access this abstract in the pubmed.

Partnerships

RECEPTA has been setting collaboration agreements with various Centers of Excellence to accomplish its research and development activities. Know More.

RECEPTA in the Press

• Cutting-edge research breaks down barriers for new drugs. Read More. • ISTO É speaks about Brazilian investigations on cancer and cardiac and cerebral diseases. Read it. • SBMF – Monoclonal antibodies as meeting theme. Read More. • Época – Guide and Thinkers. Read More.Época Negócios – The big bang of bioindustry. Read More. • DBC NEWS - Prof. Dr. Perez in an interview and report from DBC-FM. Read More.